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Plenary Lectures

Auditorium François 1er

8.7.2023

17:00 – 18:00h

FEBS Sir Hans Krebs Lecture – Opening Plenary Lecture

Chair: Janko Kos (SI)

Diet, metabolism and cancer progression
Vousden, Karen (United Kingdom)

17:00h - 18:00h

Plenary Lectures

Auditorium François 1er

8.7.2023

18:00 – 19:00h

FEBS Datta Lecture

Chair: Piotr Laidler (PL)

tRNA modifications and fidelity of decoding
Westhof, Eric (France)

18:00h - 19:00h

Symposia

Auditorium François 1er

9.7.2023

09:00 – 11:00h

Cancer and ageing

Chair: Peter Adams (US)

Mitochondrial DNA mutations in ageing and cancer - What's the connection?
Greaves, Laura (United Kingdom)

09:30h - 10:00h

Symposia

Auditorium Ronsard

9.7.2023

09:00 – 11:00h

Protein life cycle I: localisation, dynamics, functioning

Chair: Irene Diaz-Moreno (ES)

The role of highly flexible regions in orchestrating the properties of multi-domain proteins: the example of N from SARS-CoV-2
Felli, Isabella (Italy)

09:30h - 10:00h

Symposia

Auditorium Descartes

9.7.2023

09:00 – 11:00h

Climate change: biochemical CO₂fixation

Chair: Manajit Hayer-Hartl (DE)

Harnessing nature’s solutions for more efficient CO₂ fixation
Gunn, Laura (United States of America)

09:30h - 10:00h

Plenary Lectures

Auditorium François 1er

9.7.2023

15:00 – 16:00h

Molecular Oncology Lecture

Chair: Kevin Ryan (UK)

Targeting KRAS: Light at the end of the tunnel
Barbacid, Mariano (Spain)

15:00h - 16:00h

Plenary Lectures

Auditorium François 1er

9.7.2023

11:30 – 12:30h

FEBS/EMBO Women in Science Award Lecture

Chairs: Caroline Dean (UK) Gerlind Wallon (DE)

Mapping the human body: one cell at a time (pre-recorded presentation)
Teichmann, Sarah (United Kingdom)

11:30h - 12:30h

Symposia

Auditorium François 1er

9.7.2023

16:30 – 18:30h

Supramolecular assemblies I: signal transduction

Chair: Martin Picard (FR)

Misregulation of Wnt/β-catenin signaling at the plasma membrane and the regulatory role of membrane lipids in hepatocellular carcinoma
Ozhan, Gunes (Türkiye)

17:00h - 17:30h

Symposia

Auditorium Ronsard

9.7.2023

16:30 – 18:30h

Biotech solutions to current problems

Chair: Alain Marty (FR)

Designing live catalysts for large-scale environmental interventions
de Lorenzo, Victor (Spain)

17:00h - 17:30h

Symposia

Auditorium Descartes

9.7.2023

16:30 – 18:30h

Autophagy

Chair: Zvulun Elazar (IL)

Regulation of BNIP3L/NIX receptor dimerization in development-induced mitophagy
Novak Nakir, Ivana (Croatia)

18:00h - 18:15h

Symposia

Auditorium François 1er

10.7.2023

09:00 – 11:00h

Gene expression / epigenetics

Chair: Naama Barkai (IL)

The double-edged sword of transcription factor clustering
Lenstra, Tineke (Netherlands)

10:00h - 10:30h

Symposia

Auditorium Ronsard

10.7.2023

09:00 – 11:00h

Immunometabolism in cancer development and therapy

Chair: Cristina Muñoz Pinedo (ES)

Targeting immunometabolism in patient-derived breast cancer explant cultures
Klefstrom, Juha (Finland)

09:30h - 10:00h

Symposia

Auditorium Descartes

10.7.2023

09:00 – 11:00h

Chemical biology

Chair: Kathrin Lang (CH)

Chemogenetic tools for imaging, sensing and controlling cell biology
Gautier, Arnaud (France)

09:30h - 10:00h

Plenary Lectures

Auditorium François 1er

10.7.2023

11:30 – 12:30h

EMBO Lecture

Chair: Johannes Buchner (DE)

How do enhancers function to regulate embryonic development?
Furlong, Eileen (Germany)

11:30h - 12:30h

Plenary Lectures

Auditorium François 1er

10.7.2023

14:30 – 15:30h

The FEBS Journal and FEBS Letters Award Lectures

Chairs: Seamus Martin (IE) Michael Brunner (DE)

Molecular mechanism allowing Mycobacteria to evade natural antibiotics targeting the essential ClpCP degradation pathway
Weber-Ban, Eilika (Switzerland)

14:30h - 15:00h

Symposia

Auditorium François 1er

10.7.2023

16:00 – 18:00h

Cell death, and inflammation

Chair: Seamus Martin (IE)

Deconstructing inflammasomes: from mechanisms to applications
Hafner Bratkovic, Iva (Slovenia)

16:30h - 17:00h

Symposia

Auditorium Ronsard

10.7.2023

16:00 – 18:00h

Supramolecular assemblies II: RNA–protein complexes, molecular machines

Chair: Virginijus Šikšnys (LT)

mRNA scanning alteration in colorectal cancer
Hashem, Yaser (France)

16:30h - 17:00h

Symposia

Auditorium Descartes

10.7.2023

16:00 – 18:00h

Protein life cycle II: degradation

Chair: Eilika Weber-Ban (CH)

EDEM selective functions in physiological and acute ER stress
Petrescu, Stefana Maria (Romania)

16:30h - 17:00h

Symposia

Auditorium François 1er

11.7.2023

09:00 – 11:00h

Protein life cycle III: ribosomes, folding, chaperones

Chair: Ineke Braakman (NL)

Chaperoning protein self-assembly and phase transitions
Perrett, Sarah (China)

09:30h - 10:00h

Symposia

Auditorium Ronsard

11.7.2023

09:00 – 11:00h

Innate immune pathogen sensing

Chair: Miguel Soares (PT)

Regulation and function of CARD-CC / MALT1 signaling in immunity and inflammation
Beyaert, Rudi (Belgium)

09:30h - 10:00h

Plenary Lectures

Auditorium François 1er

11.7.2023

11:30 – 12:30h

FEBS Special Lecture

Chair: Jerka Dumic (HR)

The ribosome and the protein folding code of translation
Rodnina, Marina (Germany)

11:30h - 12:30h

Plenary Lectures

Auditorium François 1er

11.7.2023

14:30 – 15:30h

FEBS Theodor Bücher Lecture

Chair: Beáta Vértessy (HU)

Systematic Cell Biology - Using high throughput screens to reveal the unknown unknowns
Schuldiner, Maya (Israel)

14:30h - 15:30h

Symposia

Auditorium François 1er

11.7.2023

16:00 – 18:00h

Emerging technologies for the future

Chair: Loredano Pollegioni (IT)

Use of hyperspectral imaging in biomedical applications
Sarvazyan, Narine (United States of America)

17:00h - 17:30h

Symposia

Auditorium François 1er

12.7.2023

09:00 – 11:00h

Mitochondria in health and disease

Chair: Agnieszska Chacinska (PL)

Mitochondrial proteostasis
Rehling, Peter (Germany)

09:30h - 10:00h

Symposia

Auditorium Descartes

12.7.2023

09:00 – 11:00h

Supramolecular assemblies III: metabolons, multienzyme complexes

Chair: Anthony Pedley (US)

Genome-scale metabolic models reveal targetable vulnerabilities of metastatic colorectal cancer
Cascante, Marta (Spain)

09:30h - 10:00h

Plenary Lectures

Auditorium François 1er

12.7.2023

12:30 – 13:30h

IUBMB Lecture – Closing Plenary Lecture

Chair: Loredano Pollegioni (IT)

Turbo-charging synaptic vesicles for explosive release of neurotransmitters
Rothman, James E. (United States of America)

12:30h - 13:30h

Symposia

Auditorium Ronsard

9.7.2023

09:00 – 11:00h

Protein life cycle I: localisation, dynamics, functioning

Chair: Irene Diaz-Moreno (ES)

Protein N-terminal acetylation: machinery and impact
Arnesen, Thomas (Norway)

10:00h - 10:30h

Symposia

Auditorium Ronsard

9.7.2023

09:00 – 11:00h

Protein life cycle I: localisation, dynamics, functioning

Chair: Irene Diaz-Moreno (ES)

Structural insight into the plant PIN-FORMED auxin transporter
Ung, Kien Lam (Denmark)

10:45h - 11:00h

Symposia

Auditorium Descartes

9.7.2023

09:00 – 11:00h

Climate change: biochemical CO₂fixation

Chair: Manajit Hayer-Hartl (DE)

How pyrenoid-based CO₂-concentrating mechanisms can boost plant performance
McCormick, Alistair (United Kingdom)

10:00h - 10:30h

Symposia

Auditorium Descartes

9.7.2023

09:00 – 11:00h

Climate change: biochemical CO₂fixation

Chair: Manajit Hayer-Hartl (DE)

The evolution of the Rubiscosome
Hochberg, Georg (Germany)

10:30h - 10:45h

Symposia

Auditorium Descartes

9.7.2023

09:00 – 11:00h

Climate change: biochemical CO₂fixation

Chair: Manajit Hayer-Hartl (DE)

Rubisco regulation in crops
Carmo-Silva, Elizabete (United Kingdom)

10:45h - 11:00h

Symposia

Auditorium Ronsard

9.7.2023

16:30 – 18:30h

Biotech solutions to current problems

Chair: Alain Marty (FR)

Enzymes as game changers to address the sustainability challenge in synthesis
Hall, Mélanie (Austria)

17:30h - 18:00h

Symposia

Auditorium Ronsard

9.7.2023

16:30 – 18:30h

Biotech solutions to current problems

Chair: Alain Marty (FR)

Structural analysis of antigens on virus-like particles in vaccine formulations
Jaudzems, Kristaps (Latvia)

18:00h - 18:15h

Symposia

Auditorium François 1er

10.7.2023

09:00 – 11:00h

Gene expression / epigenetics

Chair: Naama Barkai (IL)

Understanding gene regulation using single molecule genomics
Krebs, Arnaud (Germany)

09:30h - 10:00h

Symposia

Auditorium Ronsard

10.7.2023

09:00 – 11:00h

Immunometabolism in cancer development and therapy

Chair: Cristina Muñoz Pinedo (ES)

Harnessing tumor metabolism to overcome immunosuppression
Mazzone, Massimiliano (Belgium)

10:00h - 10:30h

Symposia

Auditorium Descartes

10.7.2023

09:00 – 11:00h

Chemical biology

Chair: Kathrin Lang (CH)

Microscopic evidence for malaria infection in viscera tissue of the Medici family
Kilian, Nicole (Germany)

10:00h - 10:30h

Symposia

Auditorium Descartes

10.7.2023

09:00 – 11:00h

Chemical biology

Chair: Kathrin Lang (CH)

Ways for enhancement of anticancer action of novel synthetic and natural heterocyclic compounds
Stoika, Rostyslav (Ukraine)

10:30h - 10:45h

Symposia

Auditorium François 1er

10.7.2023

16:00 – 18:00h

Cell death, and inflammation

Chair: Seamus Martin (IE)

Gasdermin-executed pyroptosis in antitumor immunity
Shao, Feng (China)

17:00h - 17:30h

Symposia

Auditorium François 1er

10.7.2023

16:00 – 18:00h

Cell death, and inflammation

Chair: Seamus Martin (IE)

Mitochondrial nicotinic acetylcholine receptors: the role in cell survival and apoptosis (presentation cancelled)
Skok, Maryna (Ukraine)

17:30h - 17:45h

Symposia

Auditorium François 1er

11.7.2023

09:00 – 11:00h

Protein life cycle III: ribosomes, folding, chaperones

Chair: Ineke Braakman (NL)

Functional and aberrant membrane interactions of α-synuclein
De Simone, Alfonso (Italy)

10:00h - 10:30h

Symposia

Auditorium François 1er

11.7.2023

16:00 – 18:00h

Emerging technologies for the future

Chair: Loredano Pollegioni (IT)

Life beyond the pixels: single-cell analysis using deep learning and image analysis methods (pre-recorded presentation)
Horvath, Peter (Hungary)

16:30h - 17:00h

Symposia

Auditorium Ronsard

11.7.2023

16:00 – 18:00h

Cell metabolism and stress

Chair: Laszlo Nagy (HU)

Riboregulation of serine hydroxymethyltransferase, a novel mechanism controlling serine metabolism across cellular compartments
Cutruzzolà, Francesca (Italy)

16:30h - 17:00h

Symposia

Auditorium Ronsard

11.7.2023

16:00 – 18:00h

Cell metabolism and stress

Chair: Laszlo Nagy (HU)

Non-genomic integrin-mediated action of thyroid hormone on PC-12 cells during hypoxia
Barbakadze, Tamar (Georgia)

17:30h - 17:45h

Symposia

Auditorium François 1er

12.7.2023

09:00 – 11:00h

Mitochondria in health and disease

Chair: Agnieszska Chacinska (PL)

Role of mitochondrial DNA depletion in pathogenesis of mitochondrial diseases
Fakhfakh , faiza (Tunisia)

10:30h - 10:45h

Symposia

Auditorium Ronsard

12.7.2023

09:00 – 11:00h

RNA biology

Chair: Cornelia De Moor (GB)

A nuclear function for an oncogenic microRNA as a modulator of splicing
El Fatimy, Rachid (Morocco)

10:00h - 10:30h

Symposia

Auditorium Descartes

9.7.2023

16:30 – 18:30h

Autophagy

Chair: Zvulun Elazar (IL)

WIPI beta-propeller proteins in the control of autophagy and longevity
Proikas-Cezanne, Tassula (Germany)

17:00h - 17:30h

Symposia

Auditorium François 1er

10.7.2023

09:00 – 11:00h

Gene expression / epigenetics

Chair: Naama Barkai (IL)

Cell type-specific contribution of CTCF to transcriptional regulation
Pękowska, Aleksandra (Poland)

10:30h - 10:45h

Symposia

Auditorium Descartes

10.7.2023

16:00 – 18:00h

Protein life cycle II: degradation

Chair: Eilika Weber-Ban (CH)

ER-phagy and ER-to-lysosome-associated degradation
Molinari, Maurizio (Switzerland)

17:00h - 17:30h

Symposia

Auditorium Ronsard

9.7.2023

09:00 – 11:00h

Protein life cycle I: localisation, dynamics, functioning

Chair: Irene Diaz-Moreno (ES)

Mitochondrial control of nuclear condensates
Díaz-Moreno, Irene (Spain)

09:00h - 09:30h

Symposia

Auditorium Descartes

9.7.2023

09:00 – 11:00h

Climate change: biochemical CO₂fixation

Chair: Manajit Hayer-Hartl (DE)

Cellular machineries devoted to Rubisco – Nature’s predominant CO₂ fixing enzyme
Hayer-Hartl, Manajit (Germany)

09:00h - 09:30h

Symposia

Auditorium Descartes

9.7.2023

16:30 – 18:30h

Autophagy

Chair: Zvulun Elazar (IL)

Nonselective autophagosome biogenesis balances vesicle maturation with cargo inclusion
Elazar, Zvulun (Israel)

16:30h - 17:00h

Symposia

Auditorium François 1er

10.7.2023

09:00 – 11:00h

Gene expression / epigenetics

Chair: Naama Barkai (IL)

How transcription factors find their binding sites in the large genome?
barkai, Naama (Israel)

09:00h - 09:30h

Symposia

Auditorium Ronsard

10.7.2023

09:00 – 11:00h

Immunometabolism in cancer development and therapy

Chair: Cristina Muñoz Pinedo (ES)

Immunosuppression by the tumor nutrient microenvironment
Muñoz Pinedo, Cristina (Spain)

09:00h - 09:30h

Symposia

Auditorium François 1er

10.7.2023

16:00 – 18:00h

Cell death, and inflammation

Chair: Seamus Martin (IE)

Cell stress, cell death and inflammation
Martin, Seamus (Ireland)

16:00h - 16:30h

Symposia

Auditorium Ronsard

10.7.2023

16:00 – 18:00h

Supramolecular assemblies II: RNA–protein complexes, molecular machines

Chair: Virginijus Šikšnys (LT)

TnpB - a bridge between transposition and CRISPR-Cas antiviral defense
Virginijus Šikšnys (Lithuania)

16:00h - 16:30h

Symposia

Auditorium François 1er

11.7.2023

09:00 – 11:00h

Protein life cycle III: ribosomes, folding, chaperones

Chair: Ineke Braakman (NL)

Folding of ABC-transporter CFTR: a simple story
Braakman, Ineke (Netherlands)

09:00h - 09:30h

Symposia

Auditorium Ronsard

11.7.2023

09:00 – 11:00h

Innate immune pathogen sensing

Chair: Miguel Soares (PT)

Why do we survive or die from infections?
Soares, Miguel (Portugal)

09:00h - 09:30h

Symposia

Auditorium François 1er

11.7.2023

16:00 – 18:00h

Emerging technologies for the future

Chair: Loredano Pollegioni (IT)

A field of dreams: synthetic biology towards engineering microbial transformation of lignin
Pollegioni, Loredano (Italy)

16:00h - 16:30h

Symposia

Auditorium Descartes

11.7.2023

16:00 – 18:00h

Host–microbial interactions

Chair: Lena Pernas (DE)

Organelle and metabolic dynamics of the host-pathogen interaction
Pernas, Lena (Germany)

16:00h - 16:30h

Symposia

Auditorium François 1er

12.7.2023

09:00 – 11:00h

Mitochondria in health and disease

Chair: Agnieszska Chacinska (PL)

Mitochondria as regulators of cellular protein homeostasis
Chacinska, Agnieszka (Poland)

09:00h - 09:30h

Symposia

Auditorium Ronsard

11.7.2023

16:00 – 18:00h

Cell metabolism and stress

Chair: Laszlo Nagy (HU)

A multisite phosphorylation system controlling the decision between cell differentiation and proliferation enables multi-input logic gate switching
Loog, Mart (Estonia)

17:00h - 17:30h

Symposia

Auditorium Ronsard

11.7.2023

16:00 – 18:00h

Cell metabolism and stress

Chair: Laszlo Nagy (HU)

Active transcriptional repression by BACH1 as a safeguard mechanism for the functional specificity and diversity of tissue macrophages
Nagy, Laszlo (United States of America)

16:00h - 16:30h

Symposia

Auditorium François 1er

9.7.2023

16:30 – 18:30h

Supramolecular assemblies I: signal transduction

Chair: Martin Picard (FR)

Elucidating energy coupling of tripartite transport machineries in biomimetic environments
Picard, Martin (France)

16:30h - 17:00h

Symposia

Auditorium Descartes

12.7.2023

09:00 – 11:00h

Supramolecular assemblies III: metabolons, multienzyme complexes

Chair: Anthony Pedley (US)

Exploring metabolon formation in purine biosynthesis
Pedley, Anthony M. (United States of America)

09:00h - 09:30h

Symposia

Auditorium Descartes

12.7.2023

09:00 – 11:00h

Supramolecular assemblies III: metabolons, multienzyme complexes

Chair: Anthony Pedley (US)

Biological energy transduction in action - deciphering the molecular mechanism of the remarkable Complex I superfamily
Kaila, Ville R. I. (Sweden)

10:00h - 10:30h

Symposia

Auditorium Ronsard

12.7.2023

09:00 – 11:00h

RNA biology

Chair: Cornelia De Moor (GB)

Noncoding RNAs, the next generation of biomarkers and therapeutics for cardiovascular diseases
Jusic, Amela (Switzerland)

10:30h - 10:45h

Symposia

Auditorium François 1er

9.7.2023

16:30 – 18:30h

Supramolecular assemblies I: signal transduction

Chair: Martin Picard (FR)

The pleiotropic actions of arrestin proteins
Hunyady, Laszlo (Hungary)

17:30h - 18:00h

Symposia

Auditorium Descartes

11.7.2023

16:00 – 18:00h

Host–microbial interactions

Chair: Lena Pernas (DE)

Commensal genotoxin tilimycin generates colonic stem cell mutations and drives de novo emergence of antibiotic resistance in mice
Zechner, Ellen (Austria)

16:30h - 17:00h

Symposia

Auditorium Descartes

10.7.2023

09:00 – 11:00h

Chemical biology

Chair: Kathrin Lang (CH)

Expanding the genetic code - new chemistries for biology
Lang, Kathrin (Switzerland)

09:00h - 09:30h

Symposia

Auditorium Ronsard

12.7.2023

09:00 – 11:00h

RNA biology

Chair: Cornelia De Moor (GB)

Poly(A) tail metabolism as a regulator of cell growth and homeostasis
de Moor, Cornelia H. (United Kingdom)

09:00h - 09:30h

Symposia

Auditorium François 1er

12.7.2023

09:00 – 11:00h

Mitochondria in health and disease

Chair: Agnieszska Chacinska (PL)

Mitochondrial biogenesis and turnover in neurodegeneration and ageing
Tavernarakis, Nektarios (Greece)

10:00h - 10:30h

Symposia

Auditorium François 1er

9.7.2023

09:00 – 11:00h

Cancer and ageing

Chair: Peter Adams (US)

Early life influences on aging trajectories of stem cells and metabolism
Rudolph, Lenhard (Germany)

10:00h - 10:30h

Symposia

Auditorium François 1er

9.7.2023

09:00 – 11:00h

Cancer and ageing

Chair: Peter Adams (US)

Mutant p53 (mutp53)-driven HMGA1 secretion promotes pancreatic ductal adenocarcinoma (PDAC) proliferation and chemoresistance
Danzi, Federica (Italy)

10:45h - 11:00h

Symposia

Auditorium François 1er

9.7.2023

09:00 – 11:00h

Cancer and ageing

Chair: Peter Adams (US)

Understanding the role of aging in cancer
Adams, Peter (United States of America)

09:00h - 09:30h

Symposia

Auditorium Descartes

11.7.2023

09:00 – 11:00h

The exposome and cancer

Chair: Marion MacFarlane (UK)

Longitudinal profiling of the molecular features of mesothelioma – a fatal malignancy causally linked to asbestos exposure
MacFarlane, Marion (United Kingdom)

09:00h - 09:30h

Symposia

Auditorium Descartes

9.7.2023

16:30 – 18:30h

Autophagy

Chair: Zvulun Elazar (IL)

Initiation of autophagy and the role of the ATG8 conjugation machinery
Tooze, Sharon A. (United Kingdom)

17:30h - 18:00h

Symposia

Auditorium Descartes

11.7.2023

09:00 – 11:00h

The exposome and cancer

Chair: Marion MacFarlane (UK)

Formaldehyde induced endogenous DNA damage disrupts blood regeneration, nutritional homeostasis and promotes ageing
Patel, Ketan (United Kingdom)

09:30h - 10:00h

Symposia

Auditorium Descartes

10.7.2023

16:00 – 18:00h

Protein life cycle II: degradation

Chair: Eilika Weber-Ban (CH)

Cellular roles of proteasomal degradation in mycobacterial stress responses
Weber-Ban, Eilika (Switzerland)

16:00h - 16:30h

Plenary Lectures

Auditorium François 1er

10.7.2023

14:30 – 15:30h

The FEBS Journal and FEBS Letters Award Lectures

Chairs: Seamus Martin (IE) Michael Brunner (DE)

Plant lipid engineering to cut agricultural greenhouse gas emissions
Eastmond, Peter (United Kingdom)

15:00h - 15:30h

Symposia

Auditorium Ronsard

9.7.2023

16:30 – 18:30h

Biotech solutions to current problems

Chair: Alain Marty (FR)

PET recycling: From enzyme and process optimization to an industrial plant
Marty, Alain (France)

16:30h - 17:00h

Symposia

Auditorium Ronsard

10.7.2023

16:00 – 18:00h

Supramolecular assemblies II: RNA–protein complexes, molecular machines

Chair: Virginijus Šikšnys (LT)

Virus traps and other molecular machines of the future (presentation cancelled)
Dietz, Hendrik (Germany)

17:00h - 17:30h

Symposia

Auditorium Descartes

11.7.2023

09:00 – 11:00h

The exposome and cancer

Chair: Marion MacFarlane (UK)

Cell fate decisions upon exposure to ionizing radiation in tumor and normal tissue: Implications for the treatment outcome of cancer radiotherapy
Lauber, Kirsten (Germany)

10:00h - 10:30h

Symposia

Auditorium Ronsard

11.7.2023

09:00 – 11:00h

Innate immune pathogen sensing

Chair: Miguel Soares (PT)

Cell-death and innate immunity in the gut
Yabal, Monica (Germany)

10:00h - 10:30h

Symposia

Auditorium Ronsard

9.7.2023

09:00 – 11:00h

Protein life cycle I: localisation, dynamics, functioning

Chair: Irene Diaz-Moreno (ES)

Complex study on the toxic effect of SARS-CoV-2 ORF6 protein
Krachmarova, Elena (Bulgaria)

10:30h - 10:45h

Symposia

Auditorium François 1er

9.7.2023

16:30 – 18:30h

Supramolecular assemblies I: signal transduction

Chair: Martin Picard (FR)

Holdup Multiplex assay for high-throughput measurement of protein-ligand affinity constants using a mass-spectrometry readout
Monsellier, Elodie (France)

18:00h - 18:15h

Symposia

Auditorium François 1er

9.7.2023

16:30 – 18:30h

Supramolecular assemblies I: signal transduction

Chair: Martin Picard (FR)

Comparative analysis of PDZ-binding motifs in the diacylglycerol kinase family
Zambo, Boglarka (France)

18:15h - 18:30h

Symposia

Auditorium Ronsard

9.7.2023

16:30 – 18:30h

Biotech solutions to current problems

Chair: Alain Marty (FR)

Revealing the mechanisms of TnpB: biochemical characterization of DNA target recognition
Druteika, Gytis (Lithuania)

18:15h - 18:30h

Symposia

Auditorium Descartes

9.7.2023

16:30 – 18:30h

Autophagy

Chair: Zvulun Elazar (IL)

ULK1/Atg1-mediated phosphorylation regulates the interaction between GAPR-1 and Beclin 1
Kaloyanova, Dora (Netherlands)

18:15h - 18:30h

Symposia

Auditorium François 1er

10.7.2023

09:00 – 11:00h

Gene expression / epigenetics

Chair: Naama Barkai (IL)

Transcriptional co-activator PGC-1α cooperates with nuclear cap-binding proteins to activate gene expression
Rambout, Xavier (United States of America)

10:45h - 11:00h

Symposia

Auditorium Ronsard

10.7.2023

09:00 – 11:00h

Immunometabolism in cancer development and therapy

Chair: Cristina Muñoz Pinedo (ES)

Decrease of phosphocholine metabolism in 2-hydroxyflutamide-resistant prostate cancer cells
Diaz-Laviada, Ines (Spain)

10:30h - 10:45h

Symposia

Auditorium Ronsard

10.7.2023

09:00 – 11:00h

Immunometabolism in cancer development and therapy

Chair: Cristina Muñoz Pinedo (ES)

Metabolic targeting of Neuroblastoma
Kofler, Barbara (Austria)

10:45h - 11:00h

Symposia

Auditorium Descartes

10.7.2023

09:00 – 11:00h

Chemical biology

Chair: Kathrin Lang (CH)

An enhanced peptide-peptide ligation system facilitates highly efficient modular coupling for robust decoration of the cell surface
Wood, Dominic (United Kingdom)

10:45h - 11:00h

Symposia

Auditorium François 1er

10.7.2023

16:00 – 18:00h

Cell death, and inflammation

Chair: Seamus Martin (IE)

NatB-dependent acetylation protects procaspase-8 from UBR4-mediated degradation and is required for full induction of extrinsic apoptosis
Giglione, Carmela (France)

17:45h - 18:00h

Symposia

Auditorium Ronsard

10.7.2023

16:00 – 18:00h

Supramolecular assemblies II: RNA–protein complexes, molecular machines

Chair: Virginijus Šikšnys (LT)

How does a kinase and small GTPases regulate the function of scaffolding proteins? (pre-recorded presentation)
Pal, Prosenjit (United Kingdom)

17:30h - 17:45h

Symposia

Auditorium Ronsard

10.7.2023

16:00 – 18:00h

Supramolecular assemblies II: RNA–protein complexes, molecular machines

Chair: Virginijus Šikšnys (LT)

The Rab5 effector complex Rabenosyn5/Vps45 coordinates transition from membrane tethering to fusion
Caradonna, Federica (Germany)

17:45h - 18:00h

Symposia

Auditorium Descartes

10.7.2023

16:00 – 18:00h

Protein life cycle II: degradation

Chair: Eilika Weber-Ban (CH)

COP I and II dependent trafficking directs ER-associated degradation in mammalian cells
Lederkremer, Gerardo (Israel)

17:30h - 17:45h

Symposia

Auditorium Descartes

10.7.2023

16:00 – 18:00h

Protein life cycle II: degradation

Chair: Eilika Weber-Ban (CH)

Selective degradation of ARF monomers controls auxin response in Marchantia
Borst, Jan Willem (Netherlands)

17:45h - 18:00h

Symposia

Auditorium François 1er

11.7.2023

09:00 – 11:00h

Protein life cycle III: ribosomes, folding, chaperones

Chair: Ineke Braakman (NL)

GSSG at the centre of the protein oxidative folding scene
Notari, Sara (Italy)

10:30h - 10:45h

Symposia

Auditorium François 1er

11.7.2023

09:00 – 11:00h

Protein life cycle III: ribosomes, folding, chaperones

Chair: Ineke Braakman (NL)

Contribution of Heat Shock Protein A2 to the maintenance of human epidermal homeostasis
Scieglinska, Dorota (Poland)

10:45h - 11:00h

Symposia

Auditorium Ronsard

11.7.2023

09:00 – 11:00h

Innate immune pathogen sensing

Chair: Miguel Soares (PT)

Lactobacillus crispatus S-layer proteins modulate innate immune inflammation in the lower female reproductive tract.
Decout, Alexiane (United Kingdom)

10:30h - 10:45h

Symposia

Auditorium Descartes

11.7.2023

09:00 – 11:00h

The exposome and cancer

Chair: Marion MacFarlane (UK)

Chemical exposome, microenvironment & breast cancer aggressiveness
Coumoul, Xavier (France)

10:30h - 11:00h

Symposia

Auditorium François 1er

11.7.2023

16:00 – 18:00h

Emerging technologies for the future

Chair: Loredano Pollegioni (IT)

Mapping LDL receptor hot spot pathogenic residues through integration of predictive software
Larrea, Asier (Spain)

17:30h - 17:45h

Symposia

Auditorium François 1er

11.7.2023

16:00 – 18:00h

Emerging technologies for the future

Chair: Loredano Pollegioni (IT)

Profiling affinities across the interactome
GOGL, Gergo (France)

17:45h - 18:00h

Symposia

Auditorium Ronsard

11.7.2023

16:00 – 18:00h

Cell metabolism and stress

Chair: Laszlo Nagy (HU)

Regulation of the DNA-damage response by phosphorylation clusters in the p53 signaling network
Ingenhaag, Theresa (Germany)

17:45h - 18:00h

Symposia

Auditorium Descartes

11.7.2023

16:00 – 18:00h

Host–microbial interactions

Chair: Lena Pernas (DE)

Role of uracil in the antigenic variation and genetic diversity of the malaria parasite Plasmodium falciparum
Izrael, Richard (Hungary)

17:00h - 17:15h

Symposia

Auditorium Descartes

11.7.2023

16:00 – 18:00h

Host–microbial interactions

Chair: Lena Pernas (DE)

Quantifying differential modes of cytosolic access of Mycobacterium tuberculosis to the host cell cytosol
Keck, Camille (France)

17:15h - 17:30h

Plenary Lectures

Auditorium François 1er

12.7.2023

11:30 – 12:30h

FEBS Open Bio Lecture

Chair: Miguel De la Rosa (ES)

Molecular mechanisms underlying neurotransmitter release and its regulation
Rizo, Josep (United States of America)

11:30h - 12:00h

Symposia

Auditorium François 1er

12.7.2023

09:00 – 11:00h

Mitochondria in health and disease

Chair: Agnieszska Chacinska (PL)

Insights to mitochondria-regulated metabolism and mechanotransduction of hepatic cancer cells utilizing liver tumor-derived 3D cell culture system
Frtús, Adam (Czech Republic)

10:45h - 11:00h

Symposia

Auditorium Ronsard

12.7.2023

09:00 – 11:00h

RNA biology

Chair: Cornelia De Moor (GB)

The SARS-CoV-2 protein NSP2 regulates host gene expression by enhancing microRNA-induced translational silencing
Naeli, Parisa (United Kingdom)

10:45h - 11:00h

Symposia

Auditorium Descartes

12.7.2023

09:00 – 11:00h

Supramolecular assemblies III: metabolons, multienzyme complexes

Chair: Anthony Pedley (US)

Actinobacteria do it differently: surprising features of a mixed PDH/ODH metabolic supercomplex
Bellinzoni, Marco (France)

10:30h - 10:45h

Symposia

Auditorium Descartes

12.7.2023

09:00 – 11:00h

Supramolecular assemblies III: metabolons, multienzyme complexes

Chair: Anthony Pedley (US)

Engineering the yeast model Saccharomyces cerevisiae as a biofactory platform for optimizing monoterpene indole alkaloids production
Perrot, Thomas (France)

10:45h - 11:00h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

Mitochondrial transplantation enhanced the effect of cisplatin in prostate and ovarian carcinoma
Celik, Aybuke (Türkiye)

12:35h - 12:38h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

Influence of the tumor microenvironment on the formation of brain metastases by breast cancer cells
Di Russo, Sara (Italy)

12:38h - 12:41h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

A probe-based 3D co-culture screening platform to repolarize tumor-associated macrophages and cancer-associated fibroblasts
Pfirrmann, Maren (Netherlands)

12:41h - 12:44h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

MCPIP1 protein, gender and hepatocellular carcinoma - what is the relationship between them
Kwapisz, Oliwia (Poland)

12:44h - 12:47h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

Diverse tumor microenvironment composition influences the effectiveness of therapy with the use of a STING agonist and an anti-vascular compound
Czapla, Justyna (Poland)

12:47h - 12:50h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

CK2 plays a critical role in tyrosine kinase inhibitor resistance driven by the Bcr-Abl T315I mutation in chronic myeloid leukemia
Quezada Meza, Camila Paz (Italy)

12:50h - 12:53h

Speed Talks Sessions

Auditorium François 1er

9.7.2023

12:35 – 13:00h

Speed Talks Session A

Chair: Magali Blaud (FR)

Tumor-derived CTF1 is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis
Akkoc, Yunus (Türkiye)

12:53h - 12:56h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

Structural basis of Nedd4-2 regulation by 14-3-3 protein
Joshi, Rohit (Czech Republic)

12:35h - 12:38h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

LIM kinases, crucial actors of actin cytoskeleton dynamics: a new intriguing mechanism of regulation highlighted
Villalonga, Elodie (France)

12:38h - 12:41h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

The role of correlated motions of conserved polar motifs and the binding modes of agonists in the activation mechanism of G protein-coupled receptors.
Borics, Attila (Hungary)

12:41h - 12:44h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

Unravelling protein and DNA dynamics with videorate atomic force microscopy
Escolano, Joan Carles (Germany)

12:44h - 12:47h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

A tissue specific post-translational modification (PTM) map of the human proteome
Ramasamy, Pathmanaban (Belgium)

12:47h - 12:50h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

Iron overload impairs autophagy and decreases lifespan in the yeast model of Niemann-Pick type C1
Martins, Telma S. (Portugal)

12:50h - 12:53h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

Studies of three missense mutations involved in 3-phosphoglycerate dehydrogenase deficiency—a syndrome associated with reduced L-serine synthesis
Zerbini, Elena (Italy)

12:53h - 12:56h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

One step closer to the 3D bioprinted meniscus
Rybka, Jakub (Poland)

12:35h - 12:38h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

Development of immuno-PCR for sensitive quantification of SARS-CoV-2 nucleocapsid protein
Radomirovic, Mirjana (Serbia)

12:38h - 12:41h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

Bioactive natural peptides: from fighting antimicrobial resistance to anticancer opportunities
Imperlini, Esther (Italy)

12:41h - 12:44h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

Genomic and functional analysis of Bacillus velezensis P3.3S - a putative biocontrol agent of plant pathogens
Mantea, Loredana-Elena (Romania)

12:44h - 12:47h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

A system biology approach integrating cyanide assimilation into central metabolism
Blasco, Rafael (Spain)

12:47h - 12:50h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

Wood-based lignans and polyphenols improve intestinal health
Heckmann, Mara (Austria)

12:50h - 12:53h

Speed Talks Sessions

Auditorium Descartes

9.7.2023

12:35 – 13:00h

Speed Talks Session C

Chair: Johannes Buchner (DE)

Peptides obtained after in vitro digestion of intracellular proteins of S. thermophilus display anti-inflammatory activity in THP-1 cells
Allouche, Rania (France)

12:53h - 12:56h

Speed Talks Sessions

Auditorium François 1er

10.7.2023

12:35 – 13:00h

Speed Talks Session D

Chair: Alain Krol (FR)

The role of Rab27 in melanoma cell invasion and exosomal secretion
Horodecka, Katarzyna (Poland)

12:35h - 12:38h

Speed Talks Sessions

Auditorium François 1er

10.7.2023

12:35 – 13:00h

Speed Talks Session D

Chair: Alain Krol (FR)

The role of SWI/SNF chromatin remodeling complex in organ-specific transcription start site choice
Zaborowska, Magdalena (Poland)

12:38h - 12:41h

Speed Talks Sessions

Auditorium François 1er

10.7.2023

12:35 – 13:00h

Speed Talks Session D

Chair: Alain Krol (FR)

Healthy cells accelerate death of oxidatively damaged cells by blocking their transcriptional response to oxidative stress
Budimir, Jelena (Croatia)

12:41h - 12:44h

Speed Talks Sessions

Auditorium François 1er

10.7.2023

12:35 – 13:00h

Speed Talks Session D

Chair: Alain Krol (FR)

The distinct role of keratinocyte and myeloid Mcpip1 in skin inflammation
Szukała, Weronika (Poland)

12:44h - 12:48h

Speed Talks Sessions

Auditorium François 1er

10.7.2023

12:35 – 13:00h

Speed Talks Session D

Chair: Alain Krol (FR)

Molecular insights into an ancient mechanism of rapid cell death involving endoplasmic reticulum and nuclear remodeling
Chaudhuri, Arunima (Sweden)

12:48h - 12:51h

Speed Talks Sessions

Auditorium François 1er

10.7.2023

12:35 – 13:00h

Speed Talks Session D

Chair: Alain Krol (FR)

Modulation of NF-kB mediated inflammation via inhibition of p65 translocation
Zlatanova, Milena (Serbia)

12:51h - 12:54h

Speed Talks Sessions

Auditorium Ronsard

10.7.2023

12:35 – 13:00h

Speed Talks Session E

Chair: Seamus Martin (IE)

Structural and functional analysis of OrfG, a central component of the type IV secretion system of ICESt3
Robine, Maffo (France)

12:35h - 12:38h

Speed Talks Sessions

Auditorium Ronsard

10.7.2023

12:35 – 13:00h

Speed Talks Session E

Chair: Seamus Martin (IE)

Application of an innovative nanopore sequencing-based approach to identify novel circRNAs of the human PRMT1 gene in a panel of breast cancer cell lines
Papatsirou, Maria (Greece)

12:47h - 12:50h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

Deciphering of retinoid storage and metabolic pathways using bio-orthogonal chemistry-based strategies
Kindler, Alexia (France)

12:35h - 12:38h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

Engineering of chemogenetic rigid probes for polarization microscopy
Mironova, Kristina (France)

12:38h - 12:41h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

Could GroEL1 be a potential anti-tuberculosis drug target?
Zhou, Zhiyu (Belgium)

12:41h - 12:44h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

Fighting resistance to aminoglycosides - design of bacterial enzyme inhibitors
Kowalewski, Julien (France)

12:44h - 12:47h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

Selected problems/cases to stimulate collaborative learning regarding the dynamic flexibility of metabolism
Medina, Miguel Ángel (Spain)

12:47h - 12:50h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

Entrance tests: about devils or angels
Sincic, Nino (Croatia)

12:50h - 12:53h

Speed Talks Sessions

Auditorium Descartes

10.7.2023

12:35 – 13:00h

Speed Talks Session F

Chair: Hélène Munier-Lehmann (FR)

A workshop that integrates masters degree content develops soft skills for the professional future
Bajo, Ana María (Spain)

12:53h - 12:56h

Speed Talks Sessions

Auditorium François 1er

11.7.2023

12:35 – 13:00h

Speed Talks Session G

Chair: Miguel A. De la Rosa (ES)

Rewiring innate immune pathways by synthetic biology tools for the development of novel biosensors of microbial activity
Železnik Ramuta, Taja (Slovenia)

12:35h - 12:38h

Speed Talks Sessions

Auditorium François 1er

11.7.2023

12:35 – 13:00h

Speed Talks Session G

Chair: Miguel A. De la Rosa (ES)

Effect of pre-sowing seed treatment with cold plasma on secondary metabolite biosynthesis in plant: An overview of Stevia rebaudiana Bertoni case
Zukiene, Rasa (Lithuania)

12:38h - 12:41h

Speed Talks Sessions

Auditorium François 1er

11.7.2023

12:35 – 13:00h

Speed Talks Session G

Chair: Miguel A. De la Rosa (ES)

Pretreatment with a plant-derived phenolic compound confers neuroprotection in a mouse model of neonatal hypoxia-ischemia
Reyes-Corral, Marta (Spain)

12:41h - 12:44h

Speed Talks Sessions

Auditorium François 1er

11.7.2023

12:35 – 13:00h

Speed Talks Session G

Chair: Miguel A. De la Rosa (ES)

Molecular organisation of the Usher2 complex related to deafness and blindness
Wolff, Nicolas (France)

12:44h - 12:47h

Speed Talks Sessions

Auditorium François 1er

11.7.2023

12:35 – 13:00h

Speed Talks Session G

Chair: Miguel A. De la Rosa (ES)

Nanoscale outer membrane vesicles from Helicobacter pylori alter astrocyte functionality inducing neuronal degeneration
Leyton, Lisette (Chile)

12:47h - 12:50h

Speed Talks Sessions

Auditorium François 1er

11.7.2023

12:35 – 13:00h

Speed Talks Session G

Chair: Miguel A. De la Rosa (ES)

Structural dynamics of human AADC: new perspectives for severity prediction in AADC deficiency
Bisello, Giovanni (Italy)

12:50h - 12:53h

Speed Talks Sessions

Auditorium Ronsard

11.7.2023

12:35 – 13:00h

Speed Talks Session H

Chair: Kevin Ryan (UK)

Peroxi-ome – a near-complete compendium of yeast peroxisomal proteins
Peer, Lior (Israel)

12:35h - 12:38h

Speed Talks Sessions

Auditorium Ronsard

11.7.2023

12:35 – 13:00h

Speed Talks Session H

Chair: Kevin Ryan (UK)

Enhanced ER-mitochondria association and its implications in mitochondrial function, glycogen metabolism and insulin resistance
Theodoulou, Andria (Cyprus)

12:38h - 12:41h

Speed Talks Sessions

Auditorium Ronsard

11.7.2023

12:35 – 13:00h

Speed Talks Session H

Chair: Kevin Ryan (UK)

Pro-resolving lipid mediator-loaded biomimetic nanoparticles as promising carriers for inflammation resolution in atherosclerosis
Anghelache, Maria (Romania)

12:47h - 12:50h

Speed Talks Sessions

Auditorium Ronsard

11.7.2023

12:35 – 13:00h

Speed Talks Session H

Chair: Kevin Ryan (UK)

Mutant p53 stimulates mitochondrial fragmentation in pancreatic ductal adenocarcinoma (PDAC)
Fiore , Alessandra (Italy)

12:44h - 12:47h

Speed Talks Sessions

Auditorium Ronsard

11.7.2023

12:35 – 13:00h

Speed Talks Session H

Chair: Kevin Ryan (UK)

Structural characterization of starting codon recognition
Villamayor Belinchón, Laura (Spain)

12:41h - 12:44h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

The bacterial pathogen Shigella flexneri subverts the human exocyst complex to enhance intercellular spread
Ireton, Keith (New Zealand)

12:35h - 12:38h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

Pathogenic virus control of host viability at the level of the ribosome exit tunnel
Wu, Xiaofen (France)

12:38h - 12:41h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

Evolution of a protein fractal
Sendker, Franziska (Germany)

12:41h - 12:44h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale
Mazon, Hortense (France)

12:44h - 12:47h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

L-serine biosynthesis in human brain relies on a multienzymes metabolic assembly: the serinosome
Sacchi, Silvia (Italy)

12:47h - 12:50h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

Multiple electron paths associated with Flavobacterium johnsoniae respiratory Alternative Complex III
Lorencik, Katarzyna (Poland)

12:50h - 12:53h

Speed Talks Sessions

Auditorium Descartes

11.7.2023

12:35 – 13:00h

Speed Talks Session I

Chair: Beáta G. Vértessy (HU)

The cryo-EM structure of a fiber-forming bifunctional single-polypeptide enzyme explains the dual spectra of clinical presentations and of inheritance modes of its genetic disorders.
Rubio, Vicente (Spain)

12:53h - 12:56h

Speed Talks Sessions

Auditorium Ronsard

9.7.2023

12:35 – 13:00h

Speed Talks Session B

Chair: Michael Brunner (DE)

The circadian modulation of melanin biosynthesis by binding to the ROR regulatory motif in the retinal pigment epithelium
Milićević, Nemanja (Finland)

12:56h - 12:59h

Speed Talks Sessions

Auditorium Ronsard

10.7.2023

12:35 – 13:00h

Speed Talks Session E

Chair: Seamus Martin (IE)

Assembly factor of E.coli ribosomal small subunit biogenesis: structural insights
Bonnettaz, Bruno (France)

12:38h - 12:41h

Speed Talks Sessions

Auditorium Ronsard

10.7.2023

12:35 – 13:00h

Speed Talks Session E

Chair: Seamus Martin (IE)

Insulin degrading enzyme affects proteasome assembly and activity by regulating the dynamics of 20S maturation
Cavaterra, Dario (Italy)

12:41h - 12:44h

Speed Talks Sessions

Auditorium Ronsard

10.7.2023

12:35 – 13:00h

Speed Talks Session E

Chair: Seamus Martin (IE)

From mapping to mechanism: Ribosome rRNA methylation in plants
Neumann, Sara Alina (France)

12:44h - 12:47h

Speed Talks Sessions

Auditorium Ronsard

10.7.2023

12:35 – 13:00h

Speed Talks Session E

Chair: Seamus Martin (IE)

Modulation of NLRP3 inflammasome assembly, cytokine production and pyroptosis cell death: implications for a potential therapy of breast cancer
Balahura (Stămat), Liliana Roxana (Romania)

12:50h - 12:53h

Speed Talks Sessions

Auditorium Ronsard

11.7.2023

12:35 – 13:00h

Speed Talks Session H

Chair: Kevin Ryan (UK)

Boosting cholesterol efflux from foam cells by sequential administration of rHDL to deliver microRNA and to remove cholesterol in a triple-cell two-dimensional atherosclerosis model
Jebari-Benslaiman, Shifa (Spain)

12:50h - 12:53h

Symposia

Auditorium Ronsard

12.7.2023

09:00 – 11:00h

RNA biology

Chair: Cornelia De Moor (GB)

The opposing roles of the eIF4F and CCR4-NOT complexes in delivering gene expression programs
BUSHELL, MARTIN (United Kingdom)

09:30h - 10:00h

Symposia

Auditorium François 1er

9.7.2023